An image of cancer cells in mouse’s brain has been awarded first prize in an international photography competition that challenges people to think small — microscopically small.
Called the Nikon Small World competition, the contest has been celebrating the beauty in the teeny-tiny for nearly 50 years and is renowned for showcasing spectacular imagery captured with the help of a microscope.
This year’s competition attracted more than 2,100 entries from 80 countries.
The entries were judged on their originality, informational content, technical proficiency, and visual impact.
This year’s winner, which you can see at the top of this article, depicts differentiated mouse brain tumour cells.
The image was created by Dr Bruno Cisterna and Eric Vitriol from Augusta University, which took many attempts and countless hours to capture.
Dr Cisterna says the image reveals how disruptions in the cell’s cytoskeleton — the “highways” known as microtubules — can lead to diseases like Alzheimer’s and amyotrophic lateral sclerosis (ALS).
“One of the main problems with neurodegenerative diseases is that we don’t fully understand what causes them,” Dr Cisterna said.
“Differentiated cells could be used to study how mutations or toxic proteins that cause Alzheimer’s or ALS alter neuronal morphology.”
Here’s a look at the other top-ranked images.
Electric arc between a pin and a wire. (Nikon Small World 2024: Marcel Clemens)
Leaf of a cannabis plant. The bubbles inside are cannabinoid vesicles. (Nikon Small World 2024: Chris Romaine)
Section of a small intestine of a mouse. (Nikon Small World 2024: Amy Engevik)
A cluster of octopus eggs. (Nikon Small World 2024: Thomas Barlow and Connor Gibbons)
Slime mould (cribaria cancellata). (Nikon Small World 2024: Henri Koskinen)
The cross section of a European beach grass leaf. (Nikon Small World 2024: Gerhard Vlcek)
A neuron densely covered in dendritic spines from the striatum of an adult rat brain. (Nikon Small World 2024: Stephanie Huang)
Pollen in a garden spider web. (Nikon Small World 2024: John-Oliver Dum)
Spores of black truffle. (Nikon Small World 2024: Jan Martinek)
Slime mould on a rotten twig with water droplets. (Nikon Small World 2024: Ferenc Halmos)
Wing scales of a butterfly on a medical syringe needle. (Nikon Small World 2024: Daniel Knop)
The eyes of a green crab spider. (Nikon Small World 2024: Pawel Blachowicz)
Recrystallised mixture of hydroquinone and myoinositol. (Nikon Small World 2024: Marek Mis)
Isolated scales on a Madagascan sunset moth wing. (Nikon Small World 2024: Sebastien Malo)