The NFL is nothing if not unpredictable. Week 17, after all, delivered quite a few surprises, from the New York Giants stunning the Indianapolis Colts to the Kenny Pickett-led Philadelphia Eagles trouncing the Dallas Cowboys. So who, exactly, might be a safe bet for the upcoming Week 18 slate?
We’ve collected all of the best picks and gambling content from CBSSports.com and SportsLine and put them in one place, so you can get picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. Ready? Let’s jump in.
All NFL odds via SportsLine consensus odds.
Which picks can you make with confidence in Week 18? And which Super Bowl contender goes down hard? Visit SportsLine, as its incredible model simulates every NFL game 10,000 times and is up almost $7,000 for $100 players on top-rated NFL picks since its inception.
Time: Saturday, 4:30 p.m. ET (ESPN, ABC), stream on fubo (try for free)
Open: Ravens -5, O/U 46.5
Mike Tierney is 154-124-9 in his last two seasons as a SportsLine NFL expert, returning $1,586 to $100 players (every bet 1 unit) during that time. He’s also got a special pulse on the Ravens, who are already locked into the playoffs, going 53-25-2 (+2522) on his last 80 picks involving Baltimore. Check out Tierney’s full breakdown of this AFC North clash, plus his ATS projection, right here.
Time: Saturday, 8 p.m. ET (ESPN, ABC), stream on fubo (try for free)
Open: Bengals -1, O/U 43.5
NFL expert R.J. White, a Fantasy and gambling editor for CBS Sports, has gone 643-543-34 on his ATS picks from 2017-23, returning more than $4,600 to $100 players. He’s also got a distinct feel for the Steelers, going 70-40-4 (+2545) in his last 114 picks involving Pittsburgh. Does he trust Steel City to best the Bengals, who will be fighting to sneak into the playoffs? We can tell you White is leaning the Over in this matchup, but for his full breakdown and prediction, you’ll want to head over to SportsLine.
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Falcons -6.5, O/U 45.5
The SportsLine projection model simulates every NFL game 10,000 times, and it’s up well over $7,000 for $100 players on top-rated NFL picks since its inception. In Week 18, we can tell you the model is high on the Falcons (-7.5, 47.5) beating the Panthers, 29-19. The Falcons are coming off a critical overtime loss to the Washington Commanders, but they’re 4-1 in their last five games when playing as the favorite. Check out the full ATS preview and prediction for this matchup right here.
Time: Sunday, 1 p.m. ET (Fox), stream on fubo (try for free)
Open: Commanders -3, O/U 45.5
Dallas got steamrolled by the rival Philadelphia Eagles in Week 17, despite the Birds playing with not one but two different backup quarterbacks. Does CBS Sports NFL writer Tyler Sullivan like their chances to rebound at home, closing the regular season against a playoff-bound Washington squad? He does not. Sully, who’s coming off a 10-6 ATS record over the holiday slate, predicts a 27-20 win for the Commanders on the road. Check out all his Week 18 predictions right here.
Time: Sunday, 1 p.m. ET (Fox), stream on fubo (try for free)
Open: Packers -3, O/U 46
The SportsLine projection model enters Week 18 of the 2024 season on a 30-14 hot streak on top-rated NFL picks this year, boasting a stellar 68% success rate. We can tell you the simulation system likes the Packers (-9.5, 40.5) to beat the Bears by a score of 30-18. The Packers have already clinched a spot in the playoffs, but they can improve their standing with a win and a Commanders loss. The model, meanwhile, has Green Bay claiming the “W” in 80% of simulations. Catch all its Week 18 picks right here.
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Texans -3, O/U 45
“The Texans say they will play to win to try and get something good going into the playoffs, but how long will the starters play? The Titans are playing out the string and could end up with prime draft position with a loss. But something says they fight here.”
CBS Sports senior columnist Pete Prisco, who went 12-4 making straight-up picks in Week 17, likes Tennessee to make this one interesting as Houston preps for the postseason, forecasting a 20-17 upset by Brian Callahan’s squad. Check out all of Prisco’s Week 18 ATS picks right here.
Time: Sunday, 1 p.m. ET (Fox), stream on fubo (try for free)
Open: Colts -2, O/U 44.5
The Colts hope to have Anthony Richardson back under center for this essentially meaningless AFC South rematch, though Indy may be trying to ward off a major offseason overhaul in this one. Is it possible the Colts, in their desperate state, make sense as a potential parlay bet in Week 18? SportsLine has simulated every snap of Week 18 to identify top picks for a five-team parlay that could lead to a 25-1 payout. Check out the full breakdown, with analysis on every matchup, right here.
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Bills -3.5, O/U 44.5
SportsLine’s projection model is on a 210-142 roll on top-rated NFL picks that dates back to the 2017 season, and it’s also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks, beating more than 94% of CBS Sports Football Pick’em players four times during that span. Identifying top survivor picks for Week 18, we can tell you the model is shying away from the Bills (-2.5) despite Buffalo winning six of its last seven against New England. The Bills have no real incentive to play starters ahead of the playoffs. Check out SportsLine’s full ATS projection right here.
Time: Sunday, 1 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Eagles -5, O/U 43
“What the betting market is saying is that the Eagles are going to empty their bench and treat Week 18 like a preseason game, resting key players and getting ready for the wild-card round. It’s possible Tanner McKee starts at quarterback for Philadelphia, and anyone dealing with a nagging injury will probably make way for a backup to play. … [Still], if the Eagles’ first-string offensive line plays, that could potentially be enough to win against a Giants team that looked dead before last week.”
SportsLine expert and Fantasy editor R.J. White has an in-depth assessment of this NFC East rematch, with key insights and ATS projections, as part of his weekly power ratings right here at SportsLine.
Time: Sunday, 1 p.m. ET (Fox), stream on fubo (try for free)
Open: Buccaneers -2.5, O/U 43
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings offers ATS forecasts for every NFL contest. After analyzing the full Week 18 slate, the AI PickBot says the Buccaneers cover comfortably as 13.5-point home favorites against the Saints on Sunday, rating the Buccaneers cover as an A-graded pick while predicting a 30-9 outright win on average. Check out the PickBot’s full Week 18 projections right here.
Time: Sunday, 4:25 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Chiefs -4, O/U 42.5
Eric Cohen, host of the weekly “Early Edge NFL Prop Show” on YouTube, is now 146-62 (70%) on his top NFL picks since Week 4. We can tell you he likes the Broncos (-11, 40) to secure the AFC’s final playoff berth with a home win over the Chiefs: “How much does Kansas City play their starters in order to knock their division rivals out of the playoffs? The hunch here isn’t much, allowing Bo Nix to join Jayden Daniels as rookie starting quarterbacks in the playoffs.” Check out Cohen’s full breakdown, including his final-score prediction, right here at SportsLine.
Time: Sunday, 4:25 p.m. ET (CBS), stream on Paramount+ (click here)
Open: Chargers -1, O/U 43.5
Los Angeles is already locked into the playoffs, while Las Vegas is already eliminated. So what, exactly, will go down in Raiders territory, as Antonio Pierce looks to close his 2024 campaign with a victory? You might want to check with the SportsLine projection model, which is on a 64-35 roll on top-rated NFL picks dating back to 2022. You can find the model’s complete ATS simulation right here.
Time: Sunday, 4:25 p.m. ET (Fox), stream on fubo (try for free)
Open: Rams -5.5, O/U 41.5
The NFC West may be decided, with Los Angeles booked for a playoff appearance, but this divisional clash could still be spicy thanks to Jimmy Garoppolo’s anticipated start in place of Matthew Stafford. SportsLine’s simulation model, which enters Week 18 on a 30-14 hot streak on top NFL picks, has the Rams (+5.5, 39) as one of its strongest plays, projecting an L.A. cover more than 50% of the time. Check out the full analysis, plus ATS picks for every other Week 18 contest, right here.
Time: Sunday, 4:25 p.m. ET (Fox), stream on fubo (try for free)
Open: Jets -3, O/U 45
“The Dolphins caught a break in Week 17 when the kickoff temperature was 54 degrees for their game in Cleveland. However, there will be no break this week. The kickoff temperature is expected to be around 35. Also, there’s a chance that Tua Tagovailoa might not play and even if he does, he’s been dealing with a bad hip. This could be Aaron Rodgers’ final game with the Jets, and I’m going to say he goes out with a bang by eliminating the Dolphins from the playoffs.”
CBS Sports NFL writer John Breech doesn’t buy Miami as a last-gasp playoff contender, forecasting a surprise Gang Green victory in East Rutherford. Check out all his Week 18 predictions right here.
Time: Sunday, 4:25 p.m. ET (Fox), stream on fubo (try for free)
Open: 49ers -4, O/U 44.5
“The 49ers will likely be without Brock Purdy, which is a big problem. That means Josh Dobbs or Brandon Allen will start. The Cardinals played the Rams tough last week in a loss on the road and I think they will play well here. Without Purdy, the Cardinals take it.”
Both clubs are eliminated, but CBS Sports senior columnist Pete Prisco likes Arizona to claim this one at home. Check out all his Week 18 ATS projections right here.
Time: Sunday, 8:20 p.m. ET (NBC), stream on fubo (try for free)
Open: Lions -5.5, O/U 47
SportsLine expert R.J. White is a whopping 70-39-5 (+2718) on his last 114 picks in games involving the Vikings. So does he like Sam Darnold and Co. to steal the NFC North with a big win over the Lions in Motown? We can tell you he’s leaning Under on the point total in this one despite the pairing of explosive offenses, but you’ll have to check out his in-depth ATS projection for the rematch over at SportsLine.
