The No. 1 seed Kansas City Chiefs will square off against the No. 2 seed Buffalo Bills in the 2025 AFC Championship Game on Sunday, as the Chiefs try to stay on track for a third straight Super Bowl title. They are slight 2-point favorites against the Bills, who are coming off a 27-25 win over Baltimore in the Divisional Round. Buffalo notched a 30-21 win against Kansas City in November, going Over the total of 47. Which side of this AFC Championship spread should you back with your championship round NFL parlay picks?
Elsewhere, the No. 2 seed Philadelphia Eagles are 5.5-point home favorites against the No. 6 seed Washington Commanders in the NFC Championship Game odds at 3 p.m. ET on Sunday. They split the season series in their NFC East rivalry, but those meetings will be irrelevant following this week’s result. Before you make any AFC and NFC Championship Game NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the championship round of the 2025 NFL playoffs on a 31-15 betting hot streak on top-rated NFL picks this year — a stunning 67% success rate. Longer term, it is on a 211-143 roll on top-rated NFL picks that dates back to the 2017 season and a 65-36 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has scoured the championship round NFL odds and locked in five confident NFL best bets. If you successfully parlay its sports betting picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s championship round NFL picks at SportsLine.
After simulating every game 10,000 times, the model is high on the Over (48) in the NFC Championship Game 2025 between the Eagles and Commanders. These teams combined for nearly 70 points when they met last month, as Commanders rookie quarterback Jayden Daniels threw five touchdown passes to halt Philadelphia’s 10-game winning streak. Daniels is coming off another masterful performance, finishing with 299 passing yards and two touchdowns in a 45-31 win at Detroit last week.
Daniels and the Commanders have scored at least 23 points in five straight games, while Philadelphia has reached the 20-point mark in 15 consecutive games. The Eagles have the top running back in the NFL, allowing them to convert many of their drives into touchdowns. The model is anticipating another high-scoring game between these teams on Sunday, as the Over is hitting in well over 50% of simulations. See which other NFL parlay picks to make here.
The model also jumped on four other NFL bets where it says the line is way off, including an underdog that wins outright, changing the course of the 2025 NFL playoffs forever. You can only see the model’s conference championship NFL best bets and NFL parlay at SportsLine.
What are the model’s top AFC, NFC Championship Game NFL picks, which underdog pulls off an upset, and which NFL lines should you target for an epic 25-1 payout? Visit SportsLine now to see the championship round NFL best bets from a model on an 211-143 run on top-rated picks, and find out.
